I had a IS200 then IS300 then IS250 and was waiting for the IS350 to come out, but end up buying a brand new E92 335i M-SPORT after my IS250 was giving me a lot of trouble.
And to be honest I never looked back after owning the 335 since 2008 nothing has gone wrong, yes it is tuned to 400bhp and bespoke suspension but the difference in driving feel is incredible, I just replaced my rear discs and pads after 70000kls compared to every 20000kls on the Lexus same as my sisters RX350.
Maybe I will go back after I retire and get something, how knows.